Our research on diseases

The focus of CMM research has since the beginning been currently chronic diseases. We strive for a detailed molecular- and cell biological understanding of allergy, cardiovascular, rheumatic/inflammatory, endocrine and addiction disorders/diseases as well as clinical genetics.

Sweden´s health care system, CMM:s proximity to the clinical care units and its equal proximity to basic science units at Karolinska Institutet have created an internationally unique opportunity to understand the origins of disease mechanisms and outcomes of these diseases, and thus also new opportunities to develop prevention and targeted therapies. Our strategy is also to combine competence from the different research groups of CMM to foster interdisciplinary research, for example regarding the understanding of how inflammation may lead to cardiovascular disease and how the immune system interacts with the brain.

Anna Smed Sörensen Group – Respiratory and systemic immune responses in human pulmonary viral infection and inflammation

Anna Färnert Group – Global infections (specific focus on malaria)

Leo Hanke Team – Immune engineering (specific focus on emerging and re-emerging viruses)

Christopher Sundling Group – Inflammation and immune regulation during infection (specific focus on tuberculosis and malaria)

Kristina Broliden – Identifying molecular signals in the genital mucosa that determine susceptibility to sexually transmitted infections (specific focus on HIV)

Karin Loré Group – Understanding mechanisms of vaccination

Michael Sundström Group – Early drug discovery research in chronic inflammatory diseases

Eduardo Villablanca Group – Inflammatory bowel disease

Gunnar Nilsson Group – Mast cell biology (specific focus on allergy, asthma and systemic mastocytosis)

Marianne van Hage Team – Respiratory and food allergies (specific focus on severe food allergy, the alpha-Gal syndrome)

Åsa Wheelock Group – Respiratory medicine (specific focus on post COVID/long COVID syndrome)

Taras Kreslavskiy Team – Laboratory of lymphocyte biology

Per-Johan Jakobsson Group – Chronic inflammation with focus on rheumatology and cancer

B. Rethi and A. Hensvold Team – Translational arthritis research

Ioannis Parodis Team – Clinical and translational research within lupus and autoimmunity 

Leonid Padyukov Group – Genetics of autoimmune diseases (specific focus on rheumatoid arthritis, idiopathic myositis, SLE, IgA nephropathy, asthma, MCTD and multiple sclerosis)

Lars Klareskog Group – Precision medicine in prevention of rheumatoid arthritis

Jon Lampa Team – Studies of rheumatic pain

Marie Wahren Herlenius – Autoimmunity and cancer (specific focus on Sjögren’s syndrome)

Alexander Espinosa Team – Interferon-regulated genes in autoimmunity and cancer

Vivianne Malmström Group – Autoimmunity and adaptive immunity in rheumatic disease

Karine Chemin Team – T cells in rheumatic disease

Caroline Grönwall Team – B cells and autoantibodies in rheumatic disease

Ingrid Lundberg Group – Myositis – causes, clinical outcomes and treatments

Joakim Dahlin Team – Charting normal and malignant hematopoiesis

Susanne Gabrielsson Group – Extracellular vesicles in immunity

Apostolos Bossios Group – Immunoregulation of environmental-induced airway inflammation in severe asthma and bronchiectasis

Olle Kämpe Group – Autoimmune diseases (specific focus on Addison’s disease)

Magnus Bäck Group – Translational cardiology

Peder S. Olofsson Group – Cardiovascular inflammation and bioelectronic medicine

John Pernow Group – Endothelial dysfunction in atherosclerotic cardiovascular disease

Carolina Hagberg Group – Targeting lipid handling dynamics in cardiometabolic diseases

Ljubica Matic Group – Translational vascular medicine

Ulf Hedin Group – Vascular surgery

Stephen Malin Team – Lipoproteins and the immune system

Lars Maegdefessel Group – Molecular vascular medicine

Hanna Björck Group – Molecular and epidemiological studies of ascending aortic aneurysms