Lars Klareskog Group

Lars Klareskog, senior professor, lars.klareskog@ki.se

• Article: RHEUMATOLOGY. 2024;63(11):3106-3114

  Identification of circulating autoantibodies to non-modified proteins associated with ACPA status in early rheumatoid arthritis

  Lourido L; Joshua V; Hansson M; Sjoberg R; Pin E; Ruiz-Romero C; Nilsson P; Alfredsson L; Klareskog L; Blanco FJ
• Article: RHEUMATOLOGY. 2024;63(5):1221-1229

  Genome-wide investigation of persistence with methotrexate treatment in early rheumatoid arthritis

  Sysojev AO; Saevarsdottir S; Diaz-Gallo L-M; Silberberg GN; Alfredsson L; Klareskog L; Baecklund E; Bjorkman L; Kastbom A; Rantapaa-Dahlqvist S; Turesson C; Jonsdottir I; Stefansson K; Frisell T; Padyukov L; Askling J; Westerlind H
• Article: MICROBIOLOGY SPECTRUM. 2024;12(4):e0298123-e02923

  The serological immunogenicity of the third and fourth doses of COVID-19 vaccine in patients with inflammatory rheumatic diseases on different biologic or targeted DMARDs: a Swedish nationwide study (COVID-19-REUMA)

  Frodlund M; Nived P; Chatzidionysiou K; Soedergren A; Klingberg E; Hansson M; Ohlsson S; Pin E; Bengtsson A; Klareskog L; Kapetanovic M
• Article: ANNALS OF THE RHEUMATIC DISEASES. 2024;83(3):277-287

  In early rheumatoid arthritis, anticitrullinated peptide antibodies associate with low number of affected joints and rheumatoid factor associates with systemic inflammation

  Pertsinidou E; Saevarsdottir S; Manivel VA; Klareskog L; Alfredsson L; Mathsson-Alm L; Hansson M; Cornillet M; Serre G; Holmdahl R; Skriner K; Jakobsson P-J; Westerlind H; Askling J; Roennelid J
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2024;121(3):e2315354120

  Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents Infection of Omicron lineages

  Marcotte H; Cao Y; Zuo F; Simonelli L; Sammartino JC; Pedotti M; Sun R; Cassaniti I; Hagbom M; Piralla A; Yang J; Du L; Percivalle E; Bertoglio F; Schubert M; Abolhassani H; Sherina N; Guerra C; Borte S; Rezaei N; Kumagai-Braesch M; Xue Y; Su C; Yan Q; He P; Groenwall C; Klareskog L; Calzolai L; Cavalli A; Wang Q; Robbiani DF; Hust M; Shi Z; Feng L; Svensson L; Chen L; Bao L; Baldanti F; Xiao J; Qin C; Hammarstrom L; Yang X; Varani L; Xie XS; Pan-Hammarstrom Q
• Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2023;299(11):105320

  Autoreactive B cells against malondialdehyde-induced protein cross-links are present in the joint, lung, and bone marrow of rheumatoid arthritis patients

  Sahlstrom P; Joshua V; Valkovskaia V; Biese C; Stalesen R; Israelsson L; Vegvari A; Scheel-Toellner D; Klareskog L; Hansson M; Hensvold A; Malmstrom V; Gronwall C
• Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(11):1910-1922

  Rheumatoid Arthritis-Specific Autoimmunity in the Lung Before and at the Onset of Disease

  Joshua V; Loberg Haarhaus M; Hensvold A; Wahamaa H; Gerstner C; Hansson M; Israelsson L; Stalesen R; Skoeld M; Grunewald J; Klareskog L; Groenwall C; Rethi B; Catrina A; Malmstrom V
• Article: RHEUMATOLOGY. 2023;62(10):3280-3290

  Using human genetics to understand the epidemiological association between obesity, serum urate, and gout

  Zhang L; Zhang W; Xiao C; Wu X; Cui H; Yan P; Yang C; Tang M; Wang Y; Chen L; Liu Y; Zou Y; Alfredsson L; Klareskog L; Yang Y; Yao Y; Li J; Liu Z; Yang C; Jiang X; Zhang B
• Article: BRAIN BEHAVIOR AND IMMUNITY. 2023;113:212-227

  Insights into FcγR involvement in pain-like behavior induced by an RA-derived anti-modified protein autoantibody

  Jurczak A; Sandor K; Farinotti AB; Krock E; Hunt MA; Agalave NM; Barbier J; Simon N; Wang Z; Rudjito R; Vazquez-Mora JA; Martinez-Martinez A; Raoof R; Eijkelkamp N; Gronwall C; Klareskog L; Jimenez-Andrade JM; Marchand F; Svensson CI
• Article: NATURE IMMUNOLOGY. 2023;24(9):1540-1551

  Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets

  Zhao JH; Stacey D; Eriksson N; Macdonald-Dunlop E; Hedman AK; Kalnapenkis A; Enroth S; Cozzetto D; Digby-Bell J; Marten J; Folkersen L; Herder C; Jonsson L; Bergen SE; Gieger C; Needham EJ; Surendran P; Metspalu A; Milani L; Magi R; Nelis M; Hudjasov G; Paul DS; Polasek O; Thorand B; Grallert H; Roden M; Vosa U; Esko T; Hayward C; Johansson A; Gyllensten U; Powell N; Hansson O; Mattsson-Carlgren N; Joshi PK; Danesh J; Padyukov L; Klareskog L; Landen M; Wilson JF; Siegbahn A; Wallentin L; Malarstig A; Butterworth AS; Peters JE
• Article: HUMAN GENOMICS. 2023;17(1):81

  A genome-wide cross-trait analysis identifies genomic correlation, pleiotropic loci, and causal relationship between sex hormone-binding globulin and rheumatoid arthritis

  Jiang Y; Liu Q; Alfredsson L; Klareskog L; Kockum I; Jiang X
• Article: SCIENTIFIC REPORTS. 2023;13(1):10058

  Peripheral blood cellular dynamics of rheumatoid arthritis treatment informs about efficacy of response to disease modifying drugs

  Hedman AK; Winter E; Yoosuf N; Benita Y; Berg L; Brynedal B; Folkersen L; Klareskog L; Maciejewski M; Sirota-Madi A; Spector Y; Ziemek D; Padyukov L; Shen-Orr SS; Jelinsky SA
• Article: NATURE COMMUNICATIONS. 2023;14(1):3453

  Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality

  Oddsson A; Sulem P; Sveinbjornsson G; Arnadottir GM; Steinthorsdottir V; Halldorsson G; Atlason BO; Oskarsson G; Helgason H; Nielsen HS; Westergaard DA; Karjalainen J; Katrinardottir H; Fridriksdottir RB; Jensson B; Tragante VA; Ferkingstad E; Jonsson H; Gudjonsson S; Beyter D; Moore KHS; Thordardottir H; Kristmundsdottir S; Stefansson O; Rantapaa-Dahlqvist S; Sonderby IE; Didriksen MA; Stridh P; Haavik J; Tryggvadottir L; Frei O; Walters GB; Kockum I; Hjalgrim H; Olafsdottir T; Selbaek G; Nyegaard M; Erikstrup C; Brodersen T; Saevarsdottir S; Olsson T; Nielsen KR; Haraldsson A; Bruun MT; Hansen TF; Steingrimsdottir T; Jacobsen RLT; Lie R; Djurovic S; Alfredsson L; Lopez de Lapuente Portilla A; Brunak S; Melsted PV; Halldorsson B; Saemundsdottir J; Magnusson OT; Padyukov L; Banasik K; Rafnar T; Askling J; Klareskog L; Pedersen OB; Masson G; Havdahl A; Nilsson BA; Andreassen O; Daly M; Ostrowski SR; Jonsdottir I; Stefansson H; Holm H; Helgason A; Thorsteinsdottir U; Stefansson KF; Gudbjartsson D
• Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(6):872-878

  Disease Activity and Health-Related Quality of Life Among Patients With Rheumatoid Arthritis With Different Alcohol Consumption Habits

  Alfredsson L; Klareskog L; Hedstrom AK
• Article: VACCINE. 2023;41(20):3247-3257

  The impact of immunomodulating treatment on the immunogenicity of COVID-19 vaccines in patients with immune-mediated inflammatory rheumatic diseases compared to healthy controls. A Swedish nationwide study (COVID19-REUMA)

  Frodlund M; Nived P; Chatzidionysiou A; Sodergren A; Klingberg E; Bengtsson A; Hansson M; Olsson S; Pin E; Klareskog L; Kapetanovic MC
• Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(5):673-684

  Diversity and Clonality of T Cell Receptor Repertoire and Antigen Specificities in Small Joints of Early Rheumatoid Arthritis

  Turcinov S; af Klint E; Van Schoubroeck B; Kouwenhoven A; Mia S; Chemin K; Wils H; Van Hove C; De Bondt A; Keustermans K; Van Houdt J; Reumers J; Felix N; Rao NL; Peeters P; Stevenaert F; Klareskog L; McKinnon M; Baker D; Suri A; Malmstroem V
• Article: JOURNAL OF AUTOIMMUNITY. 2023;136:103022

  The human bone marrow plasma cell compartment in rheumatoid arthritis-Clonal relationships and anti-citrulline autoantibody producing cells

  Hensvold A; Horuluoglu B; Sahlstrom P; Thyagarajan R; Boada JSD; Hansson M; Mathsson-Alm L; Gerstner C; Sippl N; Israelsson L; Wedin R; Steen J; Klareskog L; Rethi B; Catrina AI; Diaz-Gallo L-M; Malmstrom V; Gronwall C
• Article: BIOMOLECULES. 2023;13(4):630

  Anti-Citrullinated Protein Antibody Reactivity towards Neutrophil-Derived Antigens: Clonal Diversity and Inter-Individual Variation

  Circiumaru A; Afonso MG; Wahamaa H; Krishnamurthy A; Hansson M; Mathsson-Alm L; Keszei M; Stalesen R; Ottosson L; de Vries C; Shelef MA; Malmstrom V; Klareskog L; Catrina AI; Gronwall C; Hensvold A; Rethi B
• Article: ANNALS OF THE RHEUMATIC DISEASES. 2023;82(3):316-323

  Occupational inhalable agents constitute major risk factors for rheumatoid arthritis, particularly in the context of genetic predisposition and smoking

  Tang B; Liu Q; Ilar A; Wiebert P; Hagg S; Padyukov L; Klareskog L; Alfredsson L; Jiang X
• Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(2):164-170

  Combination of Two Monoclonal Anti-Citrullinated Protein Antibodies Induced Tenosynovitis, Pain, and Bone Loss in Mice in a Peptidyl Arginine Deiminase-4-Dependent Manner

  Krishnamurthy A; Circiumaru A; Sun J; Kisten Y; Damberg P; Sakuraba K; Sandor K; Jarvoll P; Zhou T; Malmstrom V; Svensson CI; Hensvold A; Catrina AI; Klareskog L; Rethi B

Full list of publications.