Olle Kämpe Group
Autoimmune diseases
About
Our research group focuses mainly on model diseases, such as rare diseases like Addison’s disease.
Our research
Rare disease provides broader knowledge.
Olle Kämpe is professor of clinical endocrinology and is researching autoimmunity. By studying specific diseases such as Addison’s disease and APS-1, he wants to increase a broader understanding of how and why the body’s immune system attacks its own tissues. His research has resulted in new diagnostic methods, and may eventually lead to new treatments.
(Karolinska Institutet, 2014.)
Is it possible to stop “Addison’s disease” and other autoimmune diseases? That is the hope of Olle Kämpe, who is a clinical researcher at Karolinska Institutet. It is not known what initiates an auto immune reaction, just that it starts several years before the patients come to clinical care. Kämpe and his group has discovered that the immune system in all patients with Addison’s disease reacted to the very same substance – the enzyme 21-hydroxylase. Kämpe and this team are working on a promising treatment for patients with Addison’s. You’ll meet Olle Kämpe and his patient Eva Raffner.
(The Wallenberg Foundations, 2024.)
Group leader
Olle Kämpe, senior professor, olle.kampe@ki.se, +46852483404
Group members
Maribel Aranda-Guillén, postdoctoral researcher, maribel.aranda.guillen@ki.se
Ileana Botusan, affiliated to research, ileana.botusan@ki.se
Daniel Eriksson, affiliated to research, daniel.eriksson@ki.se
Åsa Hallgren, laboratory manager, +46852481574, asa.hallgren@ki.se
Eystein Husebye, affiliated to research, eystein.husebye@ki.se
Nils Landegren, affiliated to research, nils.landegren@ki.se
Fabian Sardh, PhD student, fabian.sardh@ki.se
Johan Svensson, affiliated to research, johan.svensson@ki.se
Selected publications
For all publications form Olle Kämpe, follow this link to Google Scholar.
All publications from group members 2023-2025
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Letter: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2025;102(1):e70039
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Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2025;40(7):860-867
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Article: SCIENCE IMMUNOLOGY. 2025;10(107):eads7377
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Article: NPJ VACCINES. 2025;10(1):88
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Article: JOURNAL OF INTERNAL MEDICINE. 2025;297(5):518-531
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Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2025;:dgaf257
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Article: LUPUS SCIENCE & MEDICINE. 2025;12(1):e001436
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Article: ARTHRITIS & RHEUMATOLOGY. 2025;77(2):212-225
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Review: FRONTIERS IN IMMUNOLOGY. 2025;16:1608934
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Article: PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES. 2025;292(2038):20241844
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Article: PSYCHONEUROENDOCRINOLOGY. 2024;170:107195
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Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2024;221(11):e20231152
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Article: SCIENTIFIC REPORTS. 2024;14(1):24512
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Article: JOURNAL OF CLINICAL INVESTIGATION. 2024;134(20):e181604
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Corrigendum: NATURE. 2024;634(8033):E5
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Article: JOURNAL OF CLINICAL INVESTIGATION. 2024;134(19):e180251
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Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2024;121(37):e2321794121
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Article: NATURE. 2024;633(8028):155-164
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Article: CELL. 2024;187(11):2817-2837.e31
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Review: LAKARTIDNINGEN. 2024;121:23111
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Article: JOURNAL OF CLINICAL INVESTIGATION. 2024;134(8):e178263
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Article: SCIENCE. 2024;383(6686):eadh4059
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Article: NPJ VACCINES. 2024;9(1):42
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Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2024;109(3):701-710
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Article: JOURNAL OF MEDICAL GENETICS. 2024;61(2):150-154
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Review: FRONTIERS IN IMMUNOLOGY. 2024;15:1501364
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Article: FRONTIERS IN IMMUNOLOGY. 2024;15:1374499
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Article: NATURE. 2023;623(7988):803-813
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Doctoral thesis: 2023
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Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2023;189(4):438-447
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Article: HGG ADVANCES. 2023;4(4):100240
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Article: EBIOMEDICINE. 2023;96:104804
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Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2023;189(2):235-241
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Article: JOURNAL OF INTERNAL MEDICINE. 2023;294(1):96-109
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Article: SCIENCE TRANSLATIONAL MEDICINE. 2023;15(701):eadg8464
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Article: JOURNAL OF CLINICAL MEDICINE. 2023;12(10):3602
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Article: CEREBRAL CORTEX. 2023;33(8):4915-4926
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Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2023;188(2):lvad010-196
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Article: JAAD CASE REPORTS. 2023;31:133-136
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Review: ENDOCRINE CONNECTIONS. 2023;12(1):e220345
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Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2023;43(1):136-150